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Workshop on Computational Systems Biology Approaches to Analysis of Genome Complexity and Regulatory Gene Networks
(20 - 25 November 2008)
Jointly organized with Bioinformatics Institute, Agency for Science, Technology and Research, Singapore
Venue: IMS Auditorium
Institute for Mathematical Sciences, NUS
3 Prince George's Park
Singapore 118402
Tel: +65 6516 1897
Venue: BII Auditorium
Bioinformatics Institute, A-Star
30 Biopolis Street #07-01, Matrix Singapore 138671
Contact person: Lina Tan
Tel: +65 6826 6440 http://www.a-star.edu.sg
Organizing Committee · Visitors and Participants · Overview · Activities · Venue
Thursday,
20 Nov 2008 |
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08:45am - 09:00am |
Registration |
Chairs: |
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09:00am - 09:15am |
Opening remarks |
09:15am - 10:00am |
Computational and experimental approaches to modeling gene regulation |
10:00am - 10:30am |
--- Coffee Break --- |
10:30am - 11:15am |
Inference of patterns and associations using dictionary models |
11:15am - 12:00nn |
The domain model for protein-protein interaction networks |
12:00nn - 01:15pm |
--- Lunch Break --- |
01:15pm - 02:00pm |
An iterative approach to weighting and expanding protein interaction networks and its impact on complex discovery |
02:00pm - 02:25pm |
Data mining in protein interaction networks |
02:25pm - 02:35pm |
TBA |
02:35pm - 03:00pm |
Computations reveals novel methods of regulation of tumor suppressors |
03:00pm - 03:35pm |
A region based nucleus detector using the mumford-Shah model |
03:35pm - 04:00pm |
--- Coffee Break --- |
04:00pm - 04:45pm |
Genome-wide identification of differential histone modification sites from ChIP-seq data using HMM |
04:45pm - 05:30pm |
Weighted gene coexpression network analysis and causality testing for finding complex disease genes (PDF) |
End of Day 1 |
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Friday,
21 Nov 2008 |
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08:45am - 09:00am |
Registration |
Chairs: |
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09:00am - 09:45am |
The mechanism of human nonhomologous DNA end joining and its role in chromosomal translocations |
09:45am - 10:30am |
Chromosomal instabilities and cancer |
10:30am - 11:00am |
--- Coffee Break --- |
11:00am - 11:45am |
Modeling and analysis of relative avidity, specificity, sensitivity of Transcription Factor-DNA binding in Genome-scale experiments |
11:45am - 12:30pm |
Chiping the human cistrome |
12:30pm - 02:00pm |
--- Lunch Break --- |
02:00pm - 02:45pm |
Tumor marker-encoding genes: a bunch of mysterious diamonds in the pile of evolutionary compost PPT |
02:45pm - 03:30pm |
Dynamics of DNA methylation |
03:30pm - 04:00pm |
--- Coffee Break --- |
04:00pm - 04:45pm |
Transcriptional and post-transcriptional control of gene expression by actin and myosin |
04:45pm - 05:30pm |
Functional analysis of OMICs data for cancer and toxicity phenotypes |
End of Day 2 |
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Saturday, 22 Nov 2008 |
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08:45am - 09:00am |
Registration |
Chairs: |
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09:00am - 09:45am |
Scalability : a statistical mechanics perspective on gene regulation and expression PPT |
09:45am - 10:30am |
The analysis of organism complexity through functional space of proteome |
10:30am - 11:00am |
--- Coffee Break --- |
11:00am - 11:45am |
In silico search for natural antisense transcripts in human genome and analysis of their expression patterns |
11:45am - 12:30pm |
Liquid association for large scale gene expression and network studies |
12:30pm - 01:45pm |
--- Lunch Break --- |
01:45pm - 02:30pm |
RNA polymerase, cell growth and proliferation: inhibitory mechanisms by the tumour suppressor glycogen synthase kinase (GSK) 3beta |
02:30pm - 03:00pm |
Thermodynamic insights based on atomistic computer simulations reveal an intricate coupling between enthalpy and entropy |
03:00pm - 03:30pm |
--- Coffee Break --- |
03:30pm - 04:15pm |
Signal transduction noise in eukaryotic cells: measurements and modeling |
End of Day 3 |
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Monday,
24 Nov 2008 |
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08:45am - 09:00am |
Registration |
Chairs: |
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09:00am - 09:45am |
Defining splicing-regulatory networks of the tissue-specific factors fox-1/2 |
09:45am - 10:30am |
Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome (PDF) |
10:30am - 11:00am |
--- Coffee Break --- |
11:00am - 11:45am |
Global and local transcriptome reprogramming in low- and high- aggressive breast cancer sub-types |
11:45am - 12:30pm |
Outcome prediction in breast and colon cancer: machine learning vs biology |
12:30pm - 02:00pm |
--- Lunch Break --- |
02:00pm - 02:45pm |
The mechanism of lymphoid gene rearrangements and their role in chromosomal translocations |
02:45pm - 03:30pm |
Bioinformatic analysis of plant microtubule and cell cycle regulating kinases |
03:30pm - 04:00pm |
--- Coffee Break --- |
04:00pm - 04:45pm |
Modeling the evolution of Alu repeats in human genome |
04:45pm - 05:15pm |
Biomolecular network reconstruction reveals mechanisms of immune reaction in colorectal cancer |
End of Day 4 |
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Tuesday, 25 Nov 2008 |
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08:45am - 09:00am |
Registration |
Chairs: |
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09:00am - 09:45am |
Network motifs performance and its possible evolutionary importance |
09:45am - 10:30am |
Hypothesis: an ectopic synthesis of the melanin in adipose may help to counteract metabolic syndrome PPT1, PPT2, PPT3 |
10:30am - 11:00am |
--- Coffee Break --- |
11:00am - 11:45am |
Network-based global inference of human disease genes |
11:45am - 12:30pm |
The biological implications of regulatory genetic variation and the definition of "normal" |
12:30pm - 01:45pm |
--- Lunch Break --- |
01:45pm - 02:30pm |
Biological context prediction from gene sequence sets within the ANNOTATOR framework |
02:30pm - 03:00pm |
Efficient watershed evolution for cellular image segmentation based on topological analysis |
03:00pm - 03:30pm |
--- Coffee Break --- |
03:30pm - 04:00pm |
Importance sampling of word patterns in DNA and protein sequences |
04:00pm - 04:45pm |
Round table discussion |
04:45pm - 04:55pm |
Closing remarks |
End of Day 5 |
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Organizing Committee · Visitors and Participants · Overview · Activities · Venue
