09:15am - 09:30am | Registration | |
09:30am - 09:45am | Opening Remarks Kwok Pui Choi, Institute for Mathematical Sciences Weng Kee Wong, University of California, Los Angeles, USA | |
09:45am | Morning Session Chair: Wei-Yin Loh, University of Wisconsin-Madison, USA | |
09:45am - 10:45am | Personalised medicine: from hype to scepticism to realism? | Stephen Senn Luxembourg Institute of Health, Luxembourg |
10:45am - 11:15am | --- Group Photo & Coffee Break --- | |
11:15am - 12:15pm | NOC: nonparametric overdose control in phase I clinical trials | Guosheng Yin The University of Hong Kong, Hong Kong |
12:15pm - 02:00pm | --- Lunch Break --- | |
02:00pm | Afternoon Session Chair: Keumhee Carriere Chough, University of Alberta, Canada | |
02:00pm - 03:00pm | Sequential designs for individualized dosing algorithms | Ying Kuen Cheung Columbia University, USA |
03:00pm - 04:00pm | BOIN: a novel platform for designing early phase single-agent and drug-combination clinical trials | Ying Yuan The University of Texas MD Anderson Cancer Center, USA |
04:00pm - 04:30pm | --- Coffee Break --- | |
04:30pm - 05:30pm | Adaptive biomarker trial designs | Adrian Mander MRC Biostatistics Unit, UK |
09:00am - 09:30am | Registration | |
09:30am | Morning Session Chair: Bee Choo Tai, National University of Singapore, Singapore | |
09:30am - 10:30am | Learning VA healthcare system through large cooperative studies (PDF) | Mei-Chiung Shih Stanford University, USA |
10:30am - 11:00am | --- Coffee Break --- | |
11:00am - 12:00pm | Multiplicity considerations in design, data monitoring and analysis of clinical trials with co-primary endpoints (PDF) | Toshimitsu Hamasaki Osaka University and National Cerebral and Cardiovascular Center, Japan |
12:00pm | Lunch at Chilli Padi Nonya Cafe (Volunteer and self paid) Address: 29 Heng Mui Keng Terrace, #06-21 (Ground Level), Singapore 119620 | |
02:00pm | Excursion to Gardens by the Bay Address: 18 Marina Gardens Drive, Singapore 018953 |
09:00am - 09:30am | Registration | |
09:30am | Morning Session Chair: Mei-Chiung Shih, Stanford University, USA | |
09:30am - 10:30am | Optimal designs for comparing (dose response) curves | Holger Dette Ruhr-Universitaet Bochum, Germany |
10:30am - 11:00am | --- Coffee Break --- | |
11:00am - 12:00pm | Equivalence of regression curves | Frank Bretz Novartis Pharma AG, Switzerland |
12:00pm - 02:00pm | --- Lunch Reception at IMS --- | |
02:00pm | Venue: Blk S16, S16-06-118, DSAP Seminar Room, Department of Statistics & Applied Probability Faculty of Science, NUS Afternoon Session Chair: Weng Kee Wong, University of California, Los Angeles, USA | |
02:00pm - 03:00pm | Design and analysis of sequential multiple-assignment randomized trials (SMARTs) (PDF) | Bibhas Chakraborty Duke-NUS Medical School, Singapore |
03:00pm - 04:00pm | Entropy learning for dynamic treatment regimes (PDF) | Jialiang Li National University of Singapore, Singapore |
04:00pm - 04:30pm | --- Coffee Break --- | |
04:30pm - 05:30pm | Methods on the usage of common controls for genetic association studies | Chaolong Wang Genome Institute of Singapore, Singapore |
09:00am - 09:30am | Registration | |
09:30am | Morning Session Chair: Ying Lu, Stanford University, USA | |
09:30am - 10:30am | A brief overview of adaptive enrichment with subpopulation selection in precision medicine (PDF) | Sue-Jang Wang U.S. Food and Drug Administration, USA |
10:30am - 11:00am | --- Coffee Break --- | |
11:00am - 12:00pm | Adaptive enrichment trials for biomarker-guided treatments (PDF) | Noah Simon University of Washington, USA |
12:00pm - 02:00pm | --- Lunch Break --- | |
02:00pm | Afternoon Session Chair: Noah Simon, University of Washington, USA | |
02:00pm - 03:00pm | Sequential multiple assignment randomization trials with enrichment design | Donglin Zeng University of North Carolina at Chapel Hill, USA |
03:00pm - 04:00pm | Designs of dose escalation studies in phase I oncology trials | Ying Lu Stanford University, USA |
04:00pm - 04:30pm | --- Coffee Break --- | |
04:30pm - 05:30pm | A nonparametric bayesian basket trial design | Peter Mueller University of Texas at Austin, USA |
09:00am - 09:30am | Registration | |
09:30am | Morning Session Chair: Frank Bretz, Novartis Pharma AG, Switzerland | |
09:30am - 10:30am | Optimal linear combination of biomarkers for multi-category diagnosis (PDF) | Yi-Hau Chen Institute of Statistical Science Academia Sinica, Taiwan |
10:30am - 11:00am | --- Coffee Break --- | |
11:00am - 12:00pm | Matched learning for estimating optimal individualized treatment rules from clinical trials and observational studies (PDF) | Yuanjia Wang Columbia University, USA |
12:00pm - 02:00pm | --- Lunch Break --- | |
02:00pm | Afternoon Session Chair: Jialiang Li, National University of Singapore, Singapore | |
02:00pm - 03:00pm | N-of-1 trials for individualized patient care (PDF) | Keumhee Carriere Chough University of Alberta, Canada |
03:00pm - 04:00pm | The promise and peril of healthcare analytics: two examples in healthcare resource planning and frequent flyer identification (PDF) | Yik Ying Teo National University of Singapore, Singapore |
04:00pm - 04:30pm | --- Coffee Break --- | |
04:30pm - 05:30pm | Analysis of massive genome, exposome and phenome data | Xihong Lin Harvard University, USA |